Technology
Our innovative HTG EdgeSeq technology powers gene expression profiling (GEP) applications including translational and clinical programs. Unlocking new insights into how the transcriptome is expressed across various sample types, disease states and research areas.
- Expression Profiling
- Sample Success
- Comparative Analysis
- Data Analytics
Comprehensive Solution for Key Insights
Gene expression profiling is the real-time measurement of cellular activity, based on the concurrent evaluation of multiple genes. The HTG EdgeSeq Platform is designed for biomarker development and can assess gene expression of hundreds to thousands of genes with high sensitivity and reproducibility.
- Expertly curated targeted panels
- Easy target quantification
- High sensitivity panels
- Save time and get data faster
Get Results with Challenging Samples
Serial testing of archived samples can lead to sample exhaustion and Quantity Not Sufficient (QNS) results, limiting the amount of information that can be gained from rare clinical specimens. HTG EdgeSeq panels require very small amounts of input material, allowing you to measure expression levels of thousands of genes, while still preserving the sample for additional follow-up studies.
- Extraction-free chemistry eliminates bias
- Maximize use of every clinical sample
- Wide range of sample types supported
Accurately Define Gene Expression Profiling
The identification of biomarkers has long been used to aid researchers in understanding cellular function in response to disease identification and progression. As with any field, the methodologies used have evolved over time to become more powerful and efficient. Below are four of the most common technologies currently used to identify and validate biomarkers and the challenges associated with each.- Targeted GEP panels
- RNA-Seq type panels
- Microarrays
- Immunohistochemistry
Visualize Breakthrough Results with Simplicity
The HTG EdgeSeq Reveal software is a powerful biostatistical and gene expression profiling set of tools for data interrogation and visualization. The HTG EdgeSeq Reveal software can identify failing samples and visualize gene signatures, including normalization and analysis of gene expression.
- Secure platform
- QC metrics
- Signature development
- Publication quality figures
