Oncology

Discover Novel Gene Expression Linkages to Develop Strategies For Diagnosis, Prevention and Treatment

Accelerate your oncology research or drug development program using the HTG EdgeSeq targeted gene expression profiling for RNA and miRNA targets. Our extraction-free chemistry provides results in less time, using less material compared to non-targeted gene expression profiling platforms such as RNA-Seq. Our platforms offer several different oncology gene panels to help target your research programs and take advantage of the HTG EdgeSeq Reveal signatures.

Quickly Identify Biomarker Using Differential Gene Expression Analysis

Compare Cohorts to Identify Key Genes and Pathway Differences

Discovery to Diagnostics on a Single Platform

Stratify Cohorts From Clinical Samples Using Differential Gene Expression

Predict Outcomes Using Gene Expression Signatures

Quickly Identify Biomarker Using Differential Gene Expression Analysis

Differential gene expression is an established method for identifying biomarkers for disease identification, sample stratification and response to therapy. The HTG EdgeSeq Oncology family of products allow you to get answers in as little as 36 hours, using a single slide of FFPE tissue.

 

Compare Cohorts to Identify Key Genes and Pathway Differences

Comparison of gene expression between study cohorts is a powerful method to identify biomarkers and molecular pathways. Once identified, biomarkers can be combined to create a signature which can then be applied to other cohort samples. In addition, the identification of molecular pathways can be useful for cohort comparison to identify gene networks involved.

 

Discovery to Diagnostics on a Single Platform

Use the HTG EdgeSeq Oncology Panels to take your biomarker research from discovery through to diagnostics on the same platform. Our expertly curated and fully validated panels have the genes you need to get your program up and running quickly and with confidence.

 

Stratify Cohorts From Clinical Samples Using Differential Gene Expression

Molecular biomarker signatures based on gene expression profiling are a commonly used method for sample comparison. The HTG EdgeSeq Panels were designed to generate biomarker signatures using gene expression profiling to enable researchers to stratify cohorts.

 

Predict Outcomes Using Gene Expression Signatures

The HTG EdgeSeq Reveal signatures are fully validated gene expression-based signatures that can be used to identify hot/cold tumors, the relative abundance of immune cell types and determine the Cell of Origin for DLBCL. The HTG EdgeSeq Reveal Software contains panel specific QC metrics to give researchers confidence in their results.

Normalization and principal component analysis tools: