miRNA

Unlock the potential of miRNA expression

MicroRNAs (miRNAs) are known regulators of transcription and have shown great potential to predict, diagnose or monitor disease. miRNAs are ideal biomarkers as they are highly stable molecules and show altered expression in different disease states and are present in biofluids including plasma/serum, saliva and urine.

Simplified miRNA Biomarker Identification and Validation

Comprehensive Targeted Panel of Whole Human miRNA Transcriptome

High Sensitivity and Reproducibility

Integrated Data Analytics Tool

Simplified miRNA Biomarker Identification and Validation

Identifying and validating miRNA expression for biological significance has provided valuable insights into the physiological progression of various diseases. Learn how HTG EdgeSeq miRNA Whole Transcriptome assay can help evaluate miRNA expression to generate signatures. Our simplified workflow can be executed in less than 36 hours with limited hands-on time.

Comprehensive Targeted Panel of miRNA Whole Transcriptome

HTG EdgeSeq miRNA Whole Transcriptome Assay (miRNA WTA) enables users to measure the expression of 2,083 human miRNA transcripts using next-generation sequencing (NGS). Our comprehensive assay is suitable for evaluation of other model organisms due to sequence homology between species.

High Sensitivity and Reproducibility

Find out how you can quickly advance your miRNA biomarker discovery using our extraction-free chemistry that does not remove small or fractured RNAs, maintaining small RNAs that can generate signal and improve sensitivity. Our assay offers high reproducibility across sample types with an intraplate variability of 0.95.

Pearson correlations of >0.95 are routinely obtained between technical replicates of FFPE

Integrated Data Analytics Tool

Characterize differential expression of miRNA using heatmaps, volcano plots and develop unique signatures using expression profiles.

Normalization and principal component analysis tools: